研究実績

研究No. 論文/著者/雑誌 対象 備考
JORTC
-RHB02
The efficacy of specialised rehabilitation using the Op-reha Guide for cancer patients in palliative care units: protocol of a multicentre, randomised controlled trial (JORTC-RHB02).

Nanako Nishiyama*, Yoshinobu Matsuda, Noriko Fujiwara, Keisuke Ariyoshi, Shunsuke Oyamada, Keiichi Narita, Ryouhei Ishii, Satoru Iwase

BMC Palliat Care. 2020 Oct 22;19(1):164. doi: 10.1186/s12904-020-00670-6.
がん
リハビリテーション
Between-group difference in mean values or changes in pain intensity? Evaluating the distribution of change from baseline in a neuropathic cancer pain clinical trial.

Matsuoka H, Morita T, Oyamada S, Yamaguchi T, Koyama A.

Ann Palliat Med. 2020 Oct 12:apm-20-930. doi: 10.21037/apm-20-930. Online ahead of print.
緩和ケア
Phase-R Safety and effectiveness of antipsychotic medication for delirium in patients with advanced cancer: A large-scale multicenter prospective observational study in real-world palliative care settings.

Maeda I, Ogawa A, Yoshiuchi K, Akechi T, Morita T, Oyamada S, Yamaguchi T, Imai K, Sakashita A, Matsumoto Y, Uemura K, Nakahara R, Iwase S; Phase-R Delirium Study Group.

Gen Hosp Psychiatry. 2020 Sep 14;67:35-41. doi: 10.1016/j.genhosppsych.2020.09.001. Online ahead of print.
緩和ケア
JORTC
-PAL12
Prevalence of Extrapyramidal Symptoms in Cancer Patients Referred to Palliative Care: A Multicenter Observational Study (JORTC PAL12)

Ishiki H, Hamano J, Nagaoka H, Matsuda Y, Tokoro A, Matsuoka H, Izumi H, Sakashita A, Kizawa Y, Oyamada S, Yamaguchi T, Iwase S.

Am J Hosp Palliat Care. 2020 Sep 17:1049909120960441. doi: 10.1177/1049909120960441. Online ahead of print.
がん
The current clinical use of adjuvant analgesics for refractory cancer pain in Japan: a nationwide cross-sectional survey.

Tagami K, Matsuoka H, Ariyoshi K, Oyamada S, Hiratsuka Y, Kizawa Y, Koyama A, Inoue A.

Jpn J Clin Oncol. 2020 Aug 31:hyaa147. doi: 10.1093/jjco/hyaa147. Online ahead of print.
Cancer Pain
JORTC
-PAL8
Predictors of duloxetine response in patients with neuropathic cancer pain: a secondary analysis of a randomized controlled trial-JORTC-PAL08 (DIRECT) study.

Matsuoka H, Iwase S, Miyaji T, Kawaguchi T, Ariyoshi K, Oyamada S, Satomi E, Ishiki H, Hasuo H, Sakuma H, Tokoro A, Matsuda Y, Tahara K, Otani H, Ohtake Y, Tsukuura H, Matsumoto Y, Hasegawa Y, Kataoka Y, Otsuka M, Sakai K, Nakura M, Morita T, Yamaguchi T, Koyama A.

Support Care Cancer. 2020 Jun;28(6):2931-2939. doi: 10.1007/s00520-019-05138-9. Epub 2019 Nov 25
緩和ケア
Assessment of Upper Limb Physiological Features in Patients with Lymphedema After Breast Surgery Using Multiple Instruments.

Motohiro Kojima, Chisako Yamauchi, Shunsuke Oyamada, Takashi Hojo, Satoru Iwase, Atsushi Naito, Kazuhiko Yamano, Shinichiro Takahashi, Atsushi Ochiai.

Lymphat Res Biol. 2020 Jun;18(3):239-246. doi: 10.1089/lrb.2019.0039. Epub 2019 Oct 29.
リンパ浮腫
Lymphedema
JORTC
-CAM03
Efficacy of oral administration of cystine and theanine in colorectal cancer patients undergoing capecitabine-based adjuvant chemotherapy after surgery: a multi-institutional, randomized, double-blinded, placebo-controlled, phase II trial (JORTC-CAM03).

Hamaguchi R, Tsuchiya T, Miyata G, Sato T, Takahashi K, Miura K, Oshio H, Ohori H, Ariyoshi K, Oyamada S, Iwase S.

Support Care Cancer. 2019 Dec 6. doi: 10.1007/s00520-019-05205-1. [Epub ahead of print]
大腸がん 味の素株式会社
JORTC
-PAL07
Morphine for dyspnoea in chronic obstructive pulmonary disease: a before-after efficacy study.

Matsuda Y, Morita T, Matsumoto H, Hosoi K, Kusama K, Kohashi Y, Morishita H, Kaku S, Ariyoshi K, Oyamada S, Inoue Y, Iwase S, Yamaguchi T, Nishikawa M.

BMJ Support Palliat Care. 2019 Nov 15:bmjspcare-2019-001929. doi: 10.1136/bmjspcare-2019-001929. Online ahead of print.
COPD
Questions Regarding the Randomized Phase II Trial of Defactinib as Maintenance Therapy in Malignant Pleural Mesothelioma.

Masuda K, Ishiki H, Oyamada S, Shimizu M, Kiuchi D, Satomi E.

J Clin Oncol. 2019 Jul 22:JCO1900891. doi: 10.1200/JCO.19.00891. [Epub ahead of print]
JORTC
-PAL08
Additive Duloxetine for Cancer-Related Neuropathic Pain Nonresponsive or Intolerant to Opioid-Pregabalin Therapy: A Randomized Controlled Trial (JORTC-PAL08).

Matsuoka H, Iwase S, Miyaji T, Kawaguchi T, Ariyoshi K, Oyamada S, Satomi E, Ishiki H, Hasuo H, Sakuma H, Tokoro A, Shinomiya T, Otani H, Ohtake Y, Tsukuura H, Matsumoto Y, Hasegawa Y, Kataoka Y, Otsuka M, Sakai K, Matsuda Y, Morita T, Koyama A, Yamaguchi T.

J Pain Symptom Manage. 2019 Jun 26. pii: S0885-3924(19)30364-1. doi: 10.1016/j.jpainsymman.2019.06.020. [Epub ahead of print]
緩和ケア 国立研究開発法人日本医療研究開発機構(AMED)革新的がん医療実用化研究事業
Attitude of Japanese palliative care specialists towards adjuvant analgesics cancer-related neuropathic pain refractory to opioid therapy: a nationwide cross-sectional survey.

Matsuoka H, Tagami K, Ariyoshi K, Oyamada S, Kizawa Y, Inoue A, Koyama A.

Jpn J Clin Oncol. 2019 May 1;49(5):486-490. doi: 10.1093/jjco/hyz002.
JORTC
-PAL05
Morphine for Refractory Dyspnea in Interstitial Lung Disease: A Phase I Study (JORTC-PAL 05).

Matsuda Y, Morita T, Miyaji T, Ogawa T, Kato K, Kawaguchi T, Tokoro A, Iwase S, Yamaguchi T, Inoue Y.

J Palliat Med. 2018 Aug 21. doi: 10.1089/jpm.2018.0272. [Epub ahead of print]
間質性肺疾患の呼吸困難
JORTC
-CAM03
Efficacy of oral administration of cystine and theanine in patients with colorectal cancer undergoing capecitabine-based adjuvant chemotherapy after surgery: study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled, phase II trial.

Hamaguchi R, Tsuchiya T, Miyata G, Sato T, Takahashi K, Ariyoshi K, Oyamada S, Iwase S.

BMJ Open. 2018 Jul 19;8(7):e021442. doi: 10.1136/bmjopen-2017-021442.
大腸がん 味の素株式会社
Decline of Physical Activity in Terminally Ill Patients Could Be Useful for Predicting Short-Term Survival.

Yasui H, Iwase S, Ariyoshi K, Nojima M, Yoshiuchi K.

Am J Hosp Palliat Care. 2018 May;35(5):749-753. doi: 10.1177/1049909117741472. Epub 2017 Nov 16.
緩和ケア
JORTC
-PAL08
Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study.

Matsuoka H, Ishiki H, Iwase S, Koyama A, Kawaguchi T, Kizawa Y, Morita T, Matsuda Y, Miyaji T, Ariyoshi K, Yamaguchi T.

BMJ Open. 2017 Aug 28;7(8):e017280. doi: 10.1136/bmjopen-2017-017280.
緩和ケア 国立研究開発法人日本医療研究開発機構(AMED)革新的がん医療実用化研究事業
JORTC
-KMP02
Additive effect of rikkunshito, an herbal medicine, on chemotherapy-induced nausea, vomiting, and anorexia in uterine cervical or corpus cancer patients treated with cisplatin and paclitaxel: results of a randomized phase II study (JORTC KMP-02).

Ohnishi S, Watari H, Kanno M, Ohba Y, Takeuchi S, Miyaji T, Oyamada S, Nomura E, Kato H, Sugiyama T, Asaka M, Sakuragi N, Yamaguchi T, Uezono Y, Iwase S.

J Gynecol Oncol. 2017 Sep;28(5):e44. doi: 10.3802/jgo.2017.28.e44. Epub 2017 Mar 17.
化学療法中の子宮がん患者の嘔気・嘔吐・食欲不振 ・厚生労働科学研究費補助金 第3次対がん総合戦略事業
・国立研究開発法人日本医療研究開発機構(AMED)革新的がん医療実用化研究事業
JORTC
-PAL09
Assessment of Cancer-Related Fatigue, Pain, and Quality of Life in Cancer Patients at Palliative Care Team Referral: A Multicenter Observational Study (JORTC PAL-09).

Satoru Iwase, Takashi Kawaguchi, Akihiro Tokoro, Kimito Yamada, Yoshiaki Kanai, Yoshinobu Matsuda, Yuko Kashiwaya, Kae Okuma, Shuji Inada, Keisuke Ariyoshi, Tempei Miyaji, Kanako Azuma, Hiroto Ishiki, Sakae Unezaki, Takuhiro Yamaguchi.

PLoS One. 2015 Aug 5;10(8):e0134022. doi: 10.1371/journal.pone.0134022. eCollection 2015.
緩和ケア
CAM01 Efficacy and safety of an amino acid jelly containing coenzyme Q10 and L-carnitine in controlling fatigue in breast cancer patients receiving chemotherapy: a multi-institutional, randomized, exploratory trial (JORTC-CAM01).

Satoru Iwase, Takashi Kawaguchi, Daisuke Yotsumoto, Takako Doi, Kyuichiro Miyara, Hiroki Odagiri, Kaoru Kitamura, Keisuke Ariyoshi, Tempei Miyaji, Hiroto Ishiki, Kenichi Inoue, Chizuko Tsutsumi, Yoshiaki Sagara, Takuhiro Yamaguchi.

Support Care in Cancer, Pubilished online :24 June 2015
乳癌 大塚製薬工場共同研究
IP study Oral Nutritional Support Can Shorten the Duration of Parenteral Hydration in End-of-Life Cancer Patients: A Randomized Controlled Trial.

Ishiki, H. Iwase, S. Gyoda, Y. Kanai, Y. Ariyoshi, K. Miyaji, T. Tahara, Y. Kawaguchi, T. Chinzei, M. Yamaguchi, T.

Nutrition and cancer December 2 2014
大塚製薬工場共同研究
Effect of Active Hexose-Correlated Compound in Women Receiving Adjuvant Chemotherapy for Breast Cancer: A Retrospective Study

Sho Hangai, Satoru Iwase, Takashi Kawaguchi, Yasunori Kogure, Tempei Miyaji, Tadaharu Matsunaga, Yoshinori Nagumo, and Takuhiro Yamaguchi.

The Journal of Alternative and Complementary Medicine.
【ePub ahead of print】
乳癌
The clinical use of Kampo medicines (traditional Japanese herbal treatments) for controlling cancer patients’ symptoms in Japan: a national cross-sectional survey

Satoru Iwase, Takuhiro Yamaguchi, Tempei Miyaji, Kiyoshi Terawaki, Akio Inui and Yasuhito Uezono.

BMC Complementary and Alternative Medicine 2012, 12:222
緩和ケア医 厚生労働省科学研究費補助金
第3次対がん総合戦略研究事業

* リストにはJORTCが任意団体の時から支援/実施していた研究も含まれています。

掲 載 日:2012年12月03日
最終更新日:2020年11月20日

 
 

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